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1 wide-range specificity
Иммунология: широкая специфичность (антисыворотки)Универсальный англо-русский словарь > wide-range specificity
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2 wide-range specificity
Англо-русский словарь по иммунологии > wide-range specificity
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3 specificity
1) ( иммунологическая) специфичность2) иммуноген. специфичность (серологически выявляемые индивидуальные детерминанты, по которым различаются аллельные формы продуктов генов главного комплекса гистосовместимости)colony specificity — колониальная специфичность ( в процессе клеточного иммунного ответа у беспозвоночных)
combinatorial specificity — специфичность комбинаторного типа ( антигенная специфичность мультимерной макромолекулы); мн. гибридные специфичности ( среди локусов главного комплекса гистосовместимости)
complementary specificity — комплементарная специфичность (комплекса идиотипической детерминанты с антидетерминантой антиидиотипического антитела)
cross-reactive specificity — 1) перекрёстная специфичность ( антигена) 2) широкая ( популяционная) специфичность ( локуса с несколькими аллелями)
dual specificity — «двойная» специфичность ( распознавания антигена)
forbidden specificity — «запрещённая» специфичность ( клона)
hybrid specificity — гибридная специфичность; мн. гибридные специфичности ( среди локусов главного комплекса гистосовместимости)
jumping specificity — «мигрирующая» ( встречающаяся на клетках различных линий дифферениировки) специфичность
link specificity — линкерная специфичность (иммунологическая специфичность химической сшивки в комплексе гаптен-носитель)
native specificity — природная ( антигенная) специфичность; специфичность нативной детерминанты ( в денатурированном белке)
ordinary specificity — ( антигенная) специфичность отдельной субъединицы, ( антигенная) специфичность индивидуальной цепи ( макромолекулы)
private specificity — уникальная специфичность (специфичность, контролируемая уникальным аллелем одного из локусов главного комплекса гистосовместимости и определяемая субтипирующей сывороткой)
public specificity — широкая ( популяционная) специфичность ( локуса с несколькими аллелями)
restricted specificity — 1) узкая специфичность ( антисыворотки) 2) уникальная специфичность (специфичность, контролируемая уникальным аллелем одного из локусов главного комплекса гистосовместимости и определяемая субтипирующей сывороткой)
triggerable specificity — специфичность индукции, триггер-специфичность (специфичность T-клеточных рецепторов в отношении антигена, определяющая возможность индукции иммунного ответа на данный антиген)
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4 широкая специфичность
Immunology: (популяционная) "public" specificity (локуса с несколькими аллелями), broad specificity (антисыворотки), (популяционная) cross-reactive specificity (локуса с несколькими аллелями), wide-range specificity (антисыворотки)Универсальный русско-английский словарь > широкая специфичность
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5 grande
adj.1 big, large.este traje me está o me queda grande this suit is too big for meun gran artista a great artistel gran favorito the firm favoriteuna gran figura a big nameuna gran parte de mi trabajo implica… a large part of my job involves…una gran responsabilidad a heavy responsibilitya lo grande in a big way, in stylegrandes almacenes department storeGran Bretaña Great Britainel Gran Cañón the Grand Canyongran danés great Danegran éxito smash (hit) (disco, libro)los Grandes Lagos the Great Lakesla Gran Muralla (China) the Great Wall (of China)el gran público the general public2 old (de edad). (Mexican Spanish, River Plate)3 fantastic(informal). ( River Plate)4 magnus, Mag, magnum.5 grand, formidable, majestical, stately.m.grandee (noble).* * *► adjetivo1 (tamaño) large, big2 (fuerte, intenso) great3 (mayor) grown-up, old, big1 (de elevada jerarquía) great\a lo grande on a grand scale, in a big wayestar grande una cosa a alguien to be too big on somebodypasarlo en grande familiar to have a great timevivir a lo grande figurado to live in style* * *adj.1) big2) large3) great* * *1. ADJ( antes de sm sing gran)1) [de tamaño] big, large; [de estatura] big, tall; [número, velocidad] high, greatviven en una casa muy grande — they live in a very big o large house
¿cómo es de grande? — how big o large is it?, what size is it?
en cantidades más grandes — in larger o greater quantities
grandísimo — enormous, huge
un esfuerzo grandísimo — an enormous effort, a huge effort
¡grandísimo tunante! — you old rogue!
hacer algo a lo grande — to do sth in style, make a splash doing sth *
2) (=importante) [artista, hazaña] great; [empresa] bighay una diferencia no muy grande — there is not a very big o great difference
3) (=mucho, muy) greatse estrenó con gran éxito — it was a great success, it went off very well
4) [en edad](=mayor)ya eres grande, Raúl — you are a big boy now, Raúl
¿qué piensas hacer cuando seas grande? — what do you want to do when you grow up?
5)¡qué grande! — Arg * how funny!
2. SMF1) (=personaje importante)2) LAm (=adulto) adult3. SF1) Arg [de lotería] first prize, big prize2) And ** (=cárcel) clink **, jail* * *I1)a) ( en dimensiones) large, big; <boca/nariz> bigb) ( en demasía) too bigme queda or me está grande — it's too big for me
quedarle grande a alguien — puesto/responsabilidad to be too much for somebody
2) ( alto) tall3) (Geog)4) ( en edad)los más grandes pueden ir solos — the older o bigger ones can go on their own
5) (delante del n)a) (notable, excelente) greatun gran hombre/vino — a great man/wine
b) ( poderoso) big6)a) (en intensidad, grado) greatme llevé un susto más grande...! — I got such a fright!
una temporada de gran éxito — a very o a highly successful season
b) ( uso enfático)7)la gran parte or mayoría de los votantes — the great o vast majority of the voters
b) ( elevado)a gran velocidad — at high o great speed
en grande: lo pasamos en grande — we had a great time (colloq)
•IImasculino, femenino1) (de la industria, el comercio) big o leading name2)a) ( mayor)quiero ir con los grandes — I want to go with the big boys/girls
b) ( adulto)•* * *= vast [vaster -comp., vastest -sup.], big [bigger -comp., biggest -sup.], bulky, considerable, deep [deeper -comp., deepest -sup.], extensive, great [greater -comp., greatest -sup.], heavy [heavier -comp., heaviest -sup.], high [higher -comp., highest -sup.], huge, large [larger -comp., largest -sup.], large scale [large-scale], tremendous, wide [wider -comp., widest -sup.], goodly [goodlier -comp., goodliest -sup.], abysmal, heavyweight [heavy weight], broad [broader -comp., broadest -sup.], of the highest order.Ex. If you add to this other access points, such as collections housed in old people's homes or day centres, prisons, hospitals, youth clubs, playgroups etc the coverage is vast.Ex. Fiction is a big item for children and also just for ordinary public library users.Ex. Like all enumerative schedules, the LC schedules are bulky, extending to some 8000 pages.Ex. The need to become familiar with different command languages for different hosts is a considerable barrier to effective retrieval.Ex. The world's largest processing department's plans and policies are always of deep interest.Ex. The minutely detailed classification is of the type appropriate to an extensive collection.Ex. Clearly, great variations can be expected between different indexing languages for different databases.Ex. In fact, the area was well served by a very good neighbourhood advice centre which had a heavy workload of advice and information-giving.Ex. Lower specificity will be associated with lower precision but high recall.Ex. A user searching for Smith's 'History as Argument' who was not sure under which subject it would be entered, would have to prowl through a huge number of cards in a card catalog to find the entry under SMITH.Ex. Serial searching for a string of characters is usually performed on a small subset of a large file.Ex. It is in the development of such large-scale services that problems are seen most acutely.Ex. There has been tremendous growth in libraries since then, but, fundamentally, it has been possible to build on the foundation that nineteenth-century heroes constructed.Ex. The method is sufficiently flexible to allow for wide modifications.Ex. However, we must not forget the book which the critics acclaim and which also sells in goodly numbers.Ex. The major problem encountered in encouraging young adults to use public libraries is the abysmal lack of specialist young adult librarians = El principal problema que se encuentra para es incentivar a los jóvenes a usar las bibliotecas públicas es la enorme falta de bibliotecarios especialistas en temas relacionados con los adolescentes.Ex. Heavyweight information technology firms such as IBM are appearing in the market and challenging traditional players.Ex. In 'upper town' streets are broad, quiet, and tree-shaded; the homes are tall and heavy and look like battleships, each anchored in its private sea of grass.Ex. I've got to tell you, and I do say this affectionately, but we're talking about a geek of the highest order.----* a grandes rasgos = broadly, rough draft.* a gran escala = large scale [large-scale], massive, on a wide scale, high-volume, wide-scale, on a broad scale, in a big way, on a grand scale.* a gran velocidad = at great speed.* a lo grande = in a big way, big time, grandly, on a grand scale.* armar un gran revuelo = set + the cat among the pigeons, put + the cat among the pigeons.* a un gran coste = at (a) great expense.* avanzar con gran dificultad = grind on.* bastante grande = largish.* calabacín grande = marrow, marrow squash.* causar una gran sensación = make + a splash.* causar un gran alboroto = make + a splash.* causar un gran revuelo = set + the cat among the pigeons, put + the cat among the pigeons, make + a splash.* celebrar a lo grande = make + a song and dance about.* con gran capacidad = capacious.* con gran colorido = brightly coloured.* con gran densidad de población = densely populated.* con gran dificultad = with great difficulty.* con gran esplendor = grandly.* con gran iluminación = brightly illuminated.* con gran motivación = highly-motivated.* con gran sentimiento = earnestly.* conseguir en gran medida + Infinitivo = go + a long way (towards/to/in) + Gerundio.* contribuir en gran medida a + Infinitivo = go + a long way (towards/to/in) + Gerundio, go far in + Gerundio, go far towards + Gerundio.* con una gran cultura = well-read.* con una gran diferencia = by a huge margin.* con una gran tradición = long-standing.* con un gran número de lectores = widely-read.* con un gran suspiro = with a deep sigh.* convertirse en un gran problema = grow to + a crisis.* correr un gran riesgo = play (for) + high stakes.* crear con gran destreza = craft.* dar un gran paso adelante = reach + milestone.* de gran ahorro energético = energy-saving.* de gran belleza = scenic.* de gran calibre = high-calibre.* de gran calidad = high-quality, high-grade [high grade], high-calibre.* de gran capacidad = large-capacity, high capacity.* de gran colorido = brightly coloured.* de gran corazón = big-hearted.* de gran efecto = wide-reaching.* de gran éxito comercial = high selling.* de gran formato = oversized.* de gran impacto = high impact [high-impact].* de gran influencia = seminal.* de gran lucidez = clear-sighted.* de gran lujo = top-class.* de gran potencia = high-powered.* de gran repercusión = far-reaching, wide-reaching, far-ranging.* de gran talento = talented.* de gran valor = highly valued, highly valuable.* de gran valor histórico = of great historical value.* de gran venta = high selling.* demasiado grande = oversized.* describir a grandes rasgos = paint + a broad picture.* desplazarse grandes distancias = travel + long distances.* ejercer una gran influencia en = play + a strong hand in.* el gran hermano = big brother.* el todo es más grande que la suma de sus partes = the whole is greater than the sum of its parts.* empresa de grandes derroches = high roller.* en gran cantidad = prodigiously.* en grandes cantidades = en masse, in good number, in bulk.* en grandes números = in record numbers, in record numbers.* en gran formato = oversize, oversized.* en gran medida = by and large, extensively, greatly, heavily, largely, to a considerable extent, to a high degree, to a large extent, tremendously, vastly, very much, to a great extent, in no small way, to any great degree, in many ways, in large part, in large measure, in no small measure, to a large degree, to a great degree.* en gran número = numerously.* en gran parte = largely, in large part, in large measure, for the most part, to a great extent, to a great degree.* en un gran aprieto = in dire straits.* en un gran apuro = in dire straits.* esperar una (gran) sorpresa = be in for a (big) surprise.* expresión típica de Gran Bretaña = Briticism.* extra grande = extra-large.* gestión de grandes extensiones para la cría de ganado = range management.* gran altura = high altitude.* gran aumento = heavy increase.* gran bebedor = heavy drinker.* gran belleza = scenic beauty.* Gran Bretaña = Britain, Great Britain.* gran calidad = high standard.* gran cantidad de = large crop of, mass of.* gran categoría = high standard.* gran cosa = big deal.* gran danés = Great Dane.* Gran Depresión, la = Depression, the, Great Depression, the.* grandes almacenes = department store.* grandes cantidades de = storerooms of, huge numbers of, huge numbers of, great numbers of.* grandes escritores, los = great imaginative writers, the.* grandes robles nacen de pequeñas bellotas = great oaks from little acorns grow.* grandes sumas de dinero = vast sums of money.* grande superficie = shopping mall, shopping complex, shopping centre.* grandes y pequeños = great and small.* grande y tenebroso = cavernous.* gran ducado = grand-duchy.* gran espectáculo = extravaganza.* gran extensión de tierra dedicada a la cría de animales de pasto = rangeland.* gran grupo = constellation.* gran mentira = big fat lie.* gran nivel = high standard.* gran número de = great numbers of.* gran pantalla de televisión = large-screen television.* gran parte = much.* gran parte de = much of.* gran peso = heavy weight.* gran placer = great pleasure.* gran potencia = great power.* gran salto adelante = giant leap, great leap forward.* gran tiburón blanco = great white shark.* gran titular = headline banner.* hacer grandes esfuerzos por = take + (great) pains to.* hacer grandes progresos = make + great strides.* hacer un gran esfuerzo = go out of + Posesivo + way to + Infinitivo.* hacer un gran negocio = make + a killing.* IGE (Integración a Gran Escala) = LSI (Large Scale Integration).* influir en gran medida = become + a force.* jaula grande para pájaros = aviary.* jugador de grandes apuestas = high roller.* la Gran Manzana = the Big Apple.* la gran mayoría de = the vast majority of, the bulk of.* levantar un gran revuelo = set + the cat among the pigeons, put + the cat among the pigeons.* llevarse una (gran) sorpresa = be in for a (big) surprise.* lo suficientemente grande = large enough, big enough.* más grande = greater.* muy grande = big time.* Nombre + a gran escala = broad scale + Nombre.* no ser gran cosa = not add up to much, add up to + nothing.* no ser una gran pérdida = be no great loss.* no significar gran cosa = not add up to much.* no suponer gran cosa = not add up to much.* no valer gran cosa = be no great shakes.* pago único y bien grande = fat lump sum.* para + Posesivo + gran sorpresa = much to + Posesivo + surprise.* pasarlo a lo grande = have + a ball, have + a whale of a time.* pasarlo en grande = have + a ball, have + a whale of a time.* pasárselo en grande = enjoy + every minute of, love + every minute of it.* Pedro el Grande = Peter the Great.* pensar a lo grande = think + big.* Pie Grande = Bigfoot, Sasquatch.* por un gran margen = by a huge margin.* producir con gran destreza = craft.* provocar un gran alboroto = make + a splash.* provocar un gran revuelo = set + the cat among the pigeons, put + the cat among the pigeons.* que le presta gran importancia a la cultura = culture-conscious.* recorrer grandes distancias = travel + long distances.* revista que tiene una gran demanda popular = mass-market journal.* ser de gran ayuda para = be a boon to.* ser de gran beneficio para = be of great benefit to.* ser una gran ayuda = be a tower of strength.* ser un gran alivio = be a welcome relief.* ser un gran apoyo = be a tower of strength.* ser un gran avance = be half the battle.* ser un gran paso adelante = be half the battle.* taza grande = mug.* tener en gran estima = have + a very high regard for.* tener gran éxito = hit + a home run, hit it out of + the park, knock it out of + the park.* tener gran importancia = be of high significance.* tener gran repercusión = be far reaching.* tener una gran tradición = have + a long ancestry.* tener un gran impacto = have + a big impact.* tomar un gran riesgo = play (for) + high stakes.* una gran cantidad de = a good deal of, a great deal of, a large degree of, a mass of, a plethora of, a supply of, a vast amount of, a city of, a wealth of, a sea of, a cascade of, an army of, a good many, a huge number of, a great number of, a multitude of, scores of, a host of, a vast corpus of, a whole host of.* una gran cantidad y variedad de = a wealth and breadth of.* una gran diversidad de = a wide range of, a broad variety of, a wide variety of, a broad range of.* una gran experiencia = a wealth of experience.* una gran extensión de = a sea of.* una gran gama de = a wide range of, a rich tapestry of, a wide band of, a broad variety of, a wide variety of, a broad range of, a whole gamut of.* una gran mayoría de = a large proportion of.* una gran parte de = a broad population of, a lion's share of.* una gran pérdida = a great loss.* una gran proporción de = a large proportion of.* una gran variedad de = a wide range of, a multiplicity of, a rich tapestry of, a plurality of, a broad variety of, a broad range of, a whole gamut of.* un gran espectro de = a wide band of.* un gran número de = a good deal of, a great deal of, a plethora of, a wide range of, a full roster of, a fair number of, a great number of, a broad variety of, a wide variety of, a broad range of, a vast corpus of.* un gran repertorio de = an arsenal of, an armoury of [armory].* un gran volumen de = a vast corpus of.* venirle Algo grande a Alguien = get + too big for + Posesivo + breeches.* WAN (red de gran alcance) = WAN (wide area network).* * *I1)a) ( en dimensiones) large, big; <boca/nariz> bigb) ( en demasía) too bigme queda or me está grande — it's too big for me
quedarle grande a alguien — puesto/responsabilidad to be too much for somebody
2) ( alto) tall3) (Geog)4) ( en edad)los más grandes pueden ir solos — the older o bigger ones can go on their own
5) (delante del n)a) (notable, excelente) greatun gran hombre/vino — a great man/wine
b) ( poderoso) big6)a) (en intensidad, grado) greatme llevé un susto más grande...! — I got such a fright!
una temporada de gran éxito — a very o a highly successful season
b) ( uso enfático)7)la gran parte or mayoría de los votantes — the great o vast majority of the voters
b) ( elevado)a gran velocidad — at high o great speed
en grande: lo pasamos en grande — we had a great time (colloq)
•IImasculino, femenino1) (de la industria, el comercio) big o leading name2)a) ( mayor)quiero ir con los grandes — I want to go with the big boys/girls
b) ( adulto)•* * *= vast [vaster -comp., vastest -sup.], big [bigger -comp., biggest -sup.], bulky, considerable, deep [deeper -comp., deepest -sup.], extensive, great [greater -comp., greatest -sup.], heavy [heavier -comp., heaviest -sup.], high [higher -comp., highest -sup.], huge, large [larger -comp., largest -sup.], large scale [large-scale], tremendous, wide [wider -comp., widest -sup.], goodly [goodlier -comp., goodliest -sup.], abysmal, heavyweight [heavy weight], broad [broader -comp., broadest -sup.], of the highest order.Ex: If you add to this other access points, such as collections housed in old people's homes or day centres, prisons, hospitals, youth clubs, playgroups etc the coverage is vast.
Ex: Fiction is a big item for children and also just for ordinary public library users.Ex: Like all enumerative schedules, the LC schedules are bulky, extending to some 8000 pages.Ex: The need to become familiar with different command languages for different hosts is a considerable barrier to effective retrieval.Ex: The world's largest processing department's plans and policies are always of deep interest.Ex: The minutely detailed classification is of the type appropriate to an extensive collection.Ex: Clearly, great variations can be expected between different indexing languages for different databases.Ex: In fact, the area was well served by a very good neighbourhood advice centre which had a heavy workload of advice and information-giving.Ex: Lower specificity will be associated with lower precision but high recall.Ex: A user searching for Smith's 'History as Argument' who was not sure under which subject it would be entered, would have to prowl through a huge number of cards in a card catalog to find the entry under SMITH.Ex: Serial searching for a string of characters is usually performed on a small subset of a large file.Ex: It is in the development of such large-scale services that problems are seen most acutely.Ex: There has been tremendous growth in libraries since then, but, fundamentally, it has been possible to build on the foundation that nineteenth-century heroes constructed.Ex: The method is sufficiently flexible to allow for wide modifications.Ex: However, we must not forget the book which the critics acclaim and which also sells in goodly numbers.Ex: The major problem encountered in encouraging young adults to use public libraries is the abysmal lack of specialist young adult librarians = El principal problema que se encuentra para es incentivar a los jóvenes a usar las bibliotecas públicas es la enorme falta de bibliotecarios especialistas en temas relacionados con los adolescentes.Ex: Heavyweight information technology firms such as IBM are appearing in the market and challenging traditional players.Ex: In 'upper town' streets are broad, quiet, and tree-shaded; the homes are tall and heavy and look like battleships, each anchored in its private sea of grass.Ex: I've got to tell you, and I do say this affectionately, but we're talking about a geek of the highest order.* a grandes rasgos = broadly, rough draft.* a gran escala = large scale [large-scale], massive, on a wide scale, high-volume, wide-scale, on a broad scale, in a big way, on a grand scale.* a gran velocidad = at great speed.* a lo grande = in a big way, big time, grandly, on a grand scale.* armar un gran revuelo = set + the cat among the pigeons, put + the cat among the pigeons.* a un gran coste = at (a) great expense.* avanzar con gran dificultad = grind on.* bastante grande = largish.* calabacín grande = marrow, marrow squash.* causar una gran sensación = make + a splash.* causar un gran alboroto = make + a splash.* causar un gran revuelo = set + the cat among the pigeons, put + the cat among the pigeons, make + a splash.* celebrar a lo grande = make + a song and dance about.* con gran capacidad = capacious.* con gran colorido = brightly coloured.* con gran densidad de población = densely populated.* con gran dificultad = with great difficulty.* con gran esplendor = grandly.* con gran iluminación = brightly illuminated.* con gran motivación = highly-motivated.* con gran sentimiento = earnestly.* conseguir en gran medida + Infinitivo = go + a long way (towards/to/in) + Gerundio.* contribuir en gran medida a + Infinitivo = go + a long way (towards/to/in) + Gerundio, go far in + Gerundio, go far towards + Gerundio.* con una gran cultura = well-read.* con una gran diferencia = by a huge margin.* con una gran tradición = long-standing.* con un gran número de lectores = widely-read.* con un gran suspiro = with a deep sigh.* convertirse en un gran problema = grow to + a crisis.* correr un gran riesgo = play (for) + high stakes.* crear con gran destreza = craft.* dar un gran paso adelante = reach + milestone.* de gran ahorro energético = energy-saving.* de gran belleza = scenic.* de gran calibre = high-calibre.* de gran calidad = high-quality, high-grade [high grade], high-calibre.* de gran capacidad = large-capacity, high capacity.* de gran colorido = brightly coloured.* de gran corazón = big-hearted.* de gran efecto = wide-reaching.* de gran éxito comercial = high selling.* de gran formato = oversized.* de gran impacto = high impact [high-impact].* de gran influencia = seminal.* de gran lucidez = clear-sighted.* de gran lujo = top-class.* de gran potencia = high-powered.* de gran repercusión = far-reaching, wide-reaching, far-ranging.* de gran talento = talented.* de gran valor = highly valued, highly valuable.* de gran valor histórico = of great historical value.* de gran venta = high selling.* demasiado grande = oversized.* describir a grandes rasgos = paint + a broad picture.* desplazarse grandes distancias = travel + long distances.* ejercer una gran influencia en = play + a strong hand in.* el gran hermano = big brother.* el todo es más grande que la suma de sus partes = the whole is greater than the sum of its parts.* empresa de grandes derroches = high roller.* en gran cantidad = prodigiously.* en grandes cantidades = en masse, in good number, in bulk.* en grandes números = in record numbers, in record numbers.* en gran formato = oversize, oversized.* en gran medida = by and large, extensively, greatly, heavily, largely, to a considerable extent, to a high degree, to a large extent, tremendously, vastly, very much, to a great extent, in no small way, to any great degree, in many ways, in large part, in large measure, in no small measure, to a large degree, to a great degree.* en gran número = numerously.* en gran parte = largely, in large part, in large measure, for the most part, to a great extent, to a great degree.* en un gran aprieto = in dire straits.* en un gran apuro = in dire straits.* esperar una (gran) sorpresa = be in for a (big) surprise.* expresión típica de Gran Bretaña = Briticism.* extra grande = extra-large.* gestión de grandes extensiones para la cría de ganado = range management.* gran altura = high altitude.* gran aumento = heavy increase.* gran bebedor = heavy drinker.* gran belleza = scenic beauty.* Gran Bretaña = Britain, Great Britain.* gran calidad = high standard.* gran cantidad de = large crop of, mass of.* gran categoría = high standard.* gran cosa = big deal.* gran danés = Great Dane.* Gran Depresión, la = Depression, the, Great Depression, the.* grandes almacenes = department store.* grandes cantidades de = storerooms of, huge numbers of, huge numbers of, great numbers of.* grandes escritores, los = great imaginative writers, the.* grandes robles nacen de pequeñas bellotas = great oaks from little acorns grow.* grandes sumas de dinero = vast sums of money.* grande superficie = shopping mall, shopping complex, shopping centre.* grandes y pequeños = great and small.* grande y tenebroso = cavernous.* gran ducado = grand-duchy.* gran espectáculo = extravaganza.* gran extensión de tierra dedicada a la cría de animales de pasto = rangeland.* gran grupo = constellation.* gran mentira = big fat lie.* gran nivel = high standard.* gran número de = great numbers of.* gran pantalla de televisión = large-screen television.* gran parte = much.* gran parte de = much of.* gran peso = heavy weight.* gran placer = great pleasure.* gran potencia = great power.* gran salto adelante = giant leap, great leap forward.* gran tiburón blanco = great white shark.* gran titular = headline banner.* hacer grandes esfuerzos por = take + (great) pains to.* hacer grandes progresos = make + great strides.* hacer un gran esfuerzo = go out of + Posesivo + way to + Infinitivo.* hacer un gran negocio = make + a killing.* IGE (Integración a Gran Escala) = LSI (Large Scale Integration).* influir en gran medida = become + a force.* jaula grande para pájaros = aviary.* jugador de grandes apuestas = high roller.* la Gran Manzana = the Big Apple.* la gran mayoría de = the vast majority of, the bulk of.* levantar un gran revuelo = set + the cat among the pigeons, put + the cat among the pigeons.* llevarse una (gran) sorpresa = be in for a (big) surprise.* lo suficientemente grande = large enough, big enough.* más grande = greater.* muy grande = big time.* Nombre + a gran escala = broad scale + Nombre.* no ser gran cosa = not add up to much, add up to + nothing.* no ser una gran pérdida = be no great loss.* no significar gran cosa = not add up to much.* no suponer gran cosa = not add up to much.* no valer gran cosa = be no great shakes.* pago único y bien grande = fat lump sum.* para + Posesivo + gran sorpresa = much to + Posesivo + surprise.* pasarlo a lo grande = have + a ball, have + a whale of a time.* pasarlo en grande = have + a ball, have + a whale of a time.* pasárselo en grande = enjoy + every minute of, love + every minute of it.* Pedro el Grande = Peter the Great.* pensar a lo grande = think + big.* Pie Grande = Bigfoot, Sasquatch.* por un gran margen = by a huge margin.* producir con gran destreza = craft.* provocar un gran alboroto = make + a splash.* provocar un gran revuelo = set + the cat among the pigeons, put + the cat among the pigeons.* que le presta gran importancia a la cultura = culture-conscious.* recorrer grandes distancias = travel + long distances.* revista que tiene una gran demanda popular = mass-market journal.* ser de gran ayuda para = be a boon to.* ser de gran beneficio para = be of great benefit to.* ser una gran ayuda = be a tower of strength.* ser un gran alivio = be a welcome relief.* ser un gran apoyo = be a tower of strength.* ser un gran avance = be half the battle.* ser un gran paso adelante = be half the battle.* taza grande = mug.* tener en gran estima = have + a very high regard for.* tener gran éxito = hit + a home run, hit it out of + the park, knock it out of + the park.* tener gran importancia = be of high significance.* tener gran repercusión = be far reaching.* tener una gran tradición = have + a long ancestry.* tener un gran impacto = have + a big impact.* tomar un gran riesgo = play (for) + high stakes.* una gran cantidad de = a good deal of, a great deal of, a large degree of, a mass of, a plethora of, a supply of, a vast amount of, a city of, a wealth of, a sea of, a cascade of, an army of, a good many, a huge number of, a great number of, a multitude of, scores of, a host of, a vast corpus of, a whole host of.* una gran cantidad y variedad de = a wealth and breadth of.* una gran diversidad de = a wide range of, a broad variety of, a wide variety of, a broad range of.* una gran experiencia = a wealth of experience.* una gran extensión de = a sea of.* una gran gama de = a wide range of, a rich tapestry of, a wide band of, a broad variety of, a wide variety of, a broad range of, a whole gamut of.* una gran mayoría de = a large proportion of.* una gran parte de = a broad population of, a lion's share of.* una gran pérdida = a great loss.* una gran proporción de = a large proportion of.* una gran variedad de = a wide range of, a multiplicity of, a rich tapestry of, a plurality of, a broad variety of, a broad range of, a whole gamut of.* un gran espectro de = a wide band of.* un gran número de = a good deal of, a great deal of, a plethora of, a wide range of, a full roster of, a fair number of, a great number of, a broad variety of, a wide variety of, a broad range of, a vast corpus of.* un gran repertorio de = an arsenal of, an armoury of [armory].* un gran volumen de = a vast corpus of.* venirle Algo grande a Alguien = get + too big for + Posesivo + breeches.* WAN (red de gran alcance) = WAN (wide area network).* * *A1 (en dimensiones) large, bigse mudaron a una casa más grande they moved to a larger o bigger housesus grandes ojos negros her big dark eyesun tipo grande, ancho de hombros a big, broad-shouldered guytiene la boca/nariz grande she has a big mouth/noseabra la boca más grande open wider2 (en demasía) too big¿esto será grande para Daniel? do you think this is too big for Daniel?estos zapatos me quedan or me están grandes these shoes are too big for mequedarle or ( Esp) venirle grande a algn «puesto/responsabilidad» to be too much for sbB (alto) tall¡qué grande está Andrés! isn't Andrés tall!, hasn't Andrés gotten* tall!C ( Geog):el Gran Buenos Aires/Bilbao Greater Buenos Aires/BilbaoD1( esp AmL) ‹niño/chico› (en edad): los más grandes pueden ir solos the older o bigger ones can go on their ownya eres grande y puedes comer solito you're a big boy now and you can feed yourselfcuando sea grande quiero ser bailarina when I grow up I want to be a ballet dancermis hijos ya son grandes my children are all grown up now2está saliendo con un tipo grande she's going out with an older guyE ( delante del n)1 (notable, excelente) greatun gran hombre/artista/vino a great man/artist/winela gran dama del teatro the grande dame of the theater2 (poderoso) biglos grandes bancos/industriales the big banks/industrialistslos grandes señores feudales the great feudal lordsa lo grande in style3(en importancia): son grandes amigos they're great friendsgrandes fumadores heavy smokersF ( fam)(increíble): ¡qué cosa más grande! ¡ya te he dicho 20 veces que no lo sé! this is unbelievable! I've told you 20 times already that I don't know!¿no es grande que ahora me echen la culpa a mí? ( iró); and now they blame me; great, isn't it? ( iro)G1 (en intensidad, grado) greatme causó una gran pena it caused me great sadnessme has dado una gran alegría you have made me very happycomió con gran apetito she ate hungrily o heartilyun día de gran calor a very hot daylos grandes fríos del 47 the great o big freeze of '47me llevé un susto más grande … I got such a frightpara mi gran vergüenza to my great embarrassmentse produjo una gran explosión there was a powerful explosiones un gran honor para mí it is a great honor* for meha sido una temporada de gran éxito it has been a very o a highly successful seasonno corre gran prisa it is not very urgentlas paredes tienen gran necesidad de una mano de pintura the walls are very much in need of a coat of paint2(uso enfático): eso es una gran verdad that is absolutely o very trueeres un grandísimo sinvergüenza you're a real swine ( colloq)ésa es la mentira más grande que he oído that's the biggest lie I've ever heardH1 (en número) ‹familia› large, big; ‹clase› bigla gran mayoría de los votantes the great o vast majority of the votersdedican gran parte de su tiempo a la investigación they devote much of o a great deal of their time to researchesto se debe en gran parte a que … this is largely due to the fact that …2(elevado): a gran velocidad at high o great speedvolar a gran altura to fly at a great heightun edificio de gran altura a very tall buildingun gran número de personas a large number of peopleobjetos de gran valor objects of great valueen grande: lo pasamos or nos divertimos en grande we had a great time ( colloq)Compuestos:masculine wide-angle lensel gran capital big businessmasculine Great Danela Gran Depresión the Great Depression( Astron): la gran explosión the Big Bangla Gran Guerra the Great Warmasculine Big Brotherel gran hermano te observa or te vigila Big Brother is watching youmasculine Grand Mastermasculine grand mastermasculine international grand masterfeminine grand operamasculine Grand Prixel gran público the general publicel gran simpático the sympathetic nervous systemmpl department storemasculine, feminineA (de la industria, el comercio) big o leading name, leading playeruno de los tres grandes de la industria automovilística one of the big three names o one of the big three in the car industryB ( esp AmL)1(mayor): quiero ir con los grandes I want to go with the big boys/girlsla grande ya está casada their eldest (daughter) is already married2 (adulto) grown-upCompuesto:(Spanish) grandee o nobleman( RPl)la grande the big prize, the jackpotsacarse la grande (literal) to win the big prize o the jackpotse sacó la grande con ese marido she hit the jackpot with that husband* * *
grande adjetivo◊ gran is used before singular nouns
1
unos grande almacenes a department store
‹ clase› big;
la gran parte or mayoría the great majority
2
◊ ¡qué grande está Andrés! isn't Andrés tall!b) ( en edad):
ya son grandes they are all grown up now
3 (Geog):
4 ( delante del n)
a lo grande in style
5
‹ explosión› powerful;◊ ¡me llevé un susto más grande … ! I got such a fright!;
una temporada de gran éxito a very o a highly successful season;
son grandes amigos they're great friends;
eso es una gran verdad that is absolutely true;
¡qué mentira más grande! that's a complete lie!b) ( elevado):◊ a gran velocidad at high o great speed;
volar a gran altura to fly at a great height;
un gran número de personas a large number of people;
objetos de gran valor objects of great value;
en grande: lo pasamos en grande we had a great time (colloq)
■ sustantivo masculino, femeninoa) ( mayor):
b) ( adulto):
grande adjetivo
1 (tamaño) big, large
grandes almacenes, department stores
2 (cantidad) large
3 fig (fuerte, intenso) great: es un gran músico, he is a great musician
♦ Locuciones: a lo grande, in style
figurado pasarlo en grande, to have a great time
' grande' also found in these entries:
Spanish:
abarcar
- alfombra
- ampliar
- ampliación
- armatoste
- así
- bastante
- bestial
- bloque
- buena
- bueno
- cabezón
- cabezona
- cabezudo
- cajón
- calabacín
- campeonato
- cantidad
- canto
- ciudad
- colosal
- consideración
- fenomenal
- formidable
- gran
- hermosa
- hermoso
- incalculable
- ingeniosa
- ingenioso
- mía
- mío
- monstruosa
- monstruoso
- monumental
- nuestra
- nuestro
- pila
- puerta
- quedar
- señor
- suficientemente
- suma
- sumo
- terraza
- tirada
- tremenda
- tremendo
- venir
- bailar
English:
abnormally
- above
- ample
- army
- awful
- bag
- baggy
- bay
- big
- boat
- border
- box
- breaker
- brush
- bulk
- carve
- cauldron
- cushion
- deposit
- enough
- extend
- grand
- great
- grow
- hers
- in
- integrate
- large
- lion
- manufacturer
- marrow
- mighty
- mine
- outrank
- overgrown
- paving stone
- place
- roller
- set on
- set upon
- slight
- spanking
- style
- tablespoonful
- tea urn
- temptation
- terrific
- time
- to
- tub
* * *♦ adj1. [de tamaño] big, large;el gran Buenos Aires/Santiago greater Buenos Aires/Santiago, the metropolitan area of Buenos Aires/Santiago;Figel cargo le viene grande he's not up to the job;Fampagó con un billete de los grandes he paid with a large notegrandes almacenes department store; Fot gran angular wide-angle lens;la Gran Barrera de Coral the Great Barrier Reef;Gran Bretaña Great Britain;el Gran Cañón (del Colorado) the Grand Canyon;gran danés Great Dane;Hist la Gran Depresión the Great Depression;gran ducado grand duchy;la Gran Explosión the Big Bang;la Gran Guerra the Great War;los Grandes Lagos the Great Lakes;gran maestro [en ajedrez] grand master;Hist Gran Mogol Mogul;la Gran Muralla (China) the Great Wall (of China);Dep Gran Premio Grand Prix; Hist el Gran Salto Adelante the Great Leap Forward;gran simio antropoide great ape;gran slam [en tenis] grand slam;Esp Com gran superficie hypermarket2. [de altura] tall;¡qué grande está tu hermano! your brother's really grown!3. [en importancia] great;una gran mujer a great woman;los grandes bancos the major banks;la gran mayoría está a favor del proyecto the great o overwhelming majority are in favour of the project;el éxito se debe en gran parte a su esfuerzo the success is largely due to her efforts, the success is in no small measure due to her efforts4. [en intensidad] great;es un gran mentiroso he's a real liar;¡qué alegría más grande! what joy!me dijeron que todavía no soy grande como para salir solo they told me I'm not big enough to go out on my own yetsiempre se llevó bien con gente más grande he always got on well with older peopleayer le hice un favor y hoy me vuelve la espalda, ¡grande! great! I did him a favour and now he doesn't want to know!9. CompFamhacer algo a lo grande to do sth in a big way o in style;vivir a lo grande to live in style;pasarlo en grande to have a great time♦ nm1. [noble] grandeeGrande de España = one of highest-ranking members of Spanish nobility2. [persona, entidad importante]uno de los grandes del sector one of the major players in the sector;los tres grandes de la liga the big three in the league;uno de los grandes de la literatura mexicana one of the big names in Mexican literature♦ nfRP [en lotería] first prize, jackpot;se sacó la grande con ese trabajo [tuvo buena suerte] she hit the jackpot with that job;con esa nuera que tiene le tocó la grande [tuvo mala suerte] you've got to feel sorry for her having a daughter-in-law like that♦ interjRP Fam [fantástico] great!* * *I adj1 big, large;me viene grande the jacket is too big for me;el cargo le viene grande the job is too much for him2:a lo grande in style;pasarlo en grande have a great timeII m/f1 L.Am. ( adulto) grown-up, adult;grandes y pequeños young and old2 ( mayor) eldest* * *1) : large, bigun libro grande: a big book2) alto: tall3) notable: greatun gran autor: a great writercon gran placer: with great pleasure5) : old, grown-uphijos grandes: grown children* * *grande adj¿es muy grande el jardín? is the garden very big?2. (número, cantidad) large3. (importante) great
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